SV EN

6α-hydroxylated bile acids mediate TGR5 signalling to improve glucose metabolism upon dietary fiber supplementation in mice

Article, Gut, February, 2023

In this article, Kassem Makki et al, show that modulation of the gut microbiota with oligofructose enriches bacteria involved in 6α-hydroxylated bile acid production and leads to TGR5-GLP1R axis activation to improve body weight and metabolism under western-style diet feeding in mice.

This article was first published online in June 2023 and was published in Gut, issue 72, February 2023.
To the article: Feb;72(2):314-324, 2023


Go back

Manage cookie settings
This website uses cookies to make our services work, and that’s why some cookies are necessary and can’t be declined. We use cookies to give you the best user experience possible. You can manage your cookies in the next session.
Cookie settings
Cookie settings
Necessary Cookies
These Cookies are necessary for our website to work and can’t be turned off. The Cookies are usually only activated when you, for example, fill out a form or create or log in to your account. They don’t track any personal information.
Performance Cookies
These Cookies help us to track the number of visitors on our webpage. They also track where our visitors came from and how they found our website. We use this information to analyze how to make our website more user-friendly for our visitors and which landing pages are most relevant for our customers. The information that we store is, for example, what pages you visit when using our website.
Marketing Cookies
We use these Cookies to analyze how we can make our advertising better. The information helps us to learn more about our visitors and makes it possible to personalize ads based on your previous use of our services.