In this paper first author Marc Schöler aim to determine how dietary fatty acid composition affects the gut microbiota profile, microbiota-mediated metabolic regulation, and development of hepatic steatosis.

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and a leading cause of liver-related mortality. Hepatic steatosis, the first step in NAFLD development, is determined by several factors including uptake and disposal of fatty acids, de novo lipogenesis and fatty acid oxidation within the liver. The composition of dietary fatty acids can affect several of these processes.

To the article "The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis" in Nature Communications